Topotecan prescribing information

Author: dipt

August undefined, 2024

WebFollowing administration of topotecan at doses of 0.5 to 1.5 mg/m 2 (0.3 to 1 times the recommended dose) administered as a 30-minute infusion, area under the curve (AUC) increases approximately proportional with dose. Distribution. Protein binding of topotecan is approximately 35%. Elimination. WebTopotecan Capsule. - Uses, Side Effects, and More. Warnings: Topotecan decreases bone marrow function. This effect may lead to a low number of blood cells such as red cells, …

Topotecan: Package Insert - Drugs.com

WebAfinitor/Afinitor Disperz prescribing information. Novartis. February 2024. 4. Alecensa prescribing information. Hoffmann-La Roche. September 2024. 5. Alunbrig prescribing information. Takeda Pharms USA. ... Hycamtin (topotecan) 0.25 mg capsule 21550080100120 M, N, O, or Y No Quantity Limit 1 mg capsule 21550080100140 M, N, O, … WebTOPOTECAN (topotecan) This product information is intended only for residents of the United States. for Healthcare professionals: TOPOTECAN, Vial U.S. Physician Prescribing … mcglincy business center

HIGHLIGHTS OF PRESCRIBING INFORMATION

Web8.1 Pregnancy. Risk Summary. Based on animal data and its mechanism of action, Topotecan Injection can cause fetal harm when administered to a pregnant woman. There are no available clinical data on the use of topotecan in pregnancy. Topotecan caused embryolethality, fetotoxicity, and teratogenicity in rats and rabbits when administered … Web16 HOW SUPPLIED/STORAGE AND HANDLING. Topotecan Injection is supplied in 4 mg/4 mL (1 mg/mL topotecan free base) single-dose vials. Each vial contains 4 mL of the sterile, clear, yellow to yellow-green solution. WebSep 13, 2024 · Mouth irritation or mouth sores. Constipation, diarrhea, throwing up, and upset stomach are common with topotecan injection. If these happen, talk with your doctor about ways to lower these side effects. Call your doctor right away if any of these effects bother you, do not go away, or get very bad. These are not all of the side effects that ... libertarian official website

Topotecan Side Effects: Common, Severe, Long Term - Drugs.com

Topotecan - Memorial Sloan Kettering Cancer Center

WebMar 22, 2024 · Alternatively, administer G-CSF 24 hours after the final dose of topotecan in the subsequent treatment course (i.e., beginning on day 4 of the 21-day treatment … Webtopotecan injection Quick Finder. Pfizer samples (for eligible HCPs) Requests for samples of prescription medications can be made by contacting Pfizer for Professionals at 1-800-505-4426 or by visiting the PfizerPro website www.pfizerpro.com. Report an adverse event or concern about the quality of a Pfizer product. mcglincy murder 1896WebPlease see full Prescribing Information for additional Important Safety Information. INDICATIONS. MVASI® is a vascular endothelial growth factor inhibitor indicated for the treatment of: ... MVASI®, in combination with paclitaxel and cisplatin or paclitaxel and topotecan, is indicated for the treatment of patients with persistent, recurrent ... mcglincy and ingolia 2017

"WebApr 28, 2024 · When topotecan is used in combination with cisplatin, the full prescribing information for cisplatin should be consulted. Prior to administration of the first course of topotecan, patients must have a baseline neutrophil count of ≥1.5 x 10 9 /l, a platelet count of ≥100 x 10 9 /l and a haemoglobin level of ≥9 g/dl (after transfusion if ... " - Topotecan prescribing information

Topotecan prescribing information

topotecan injection Pfizer Medical Information - US

WebThe recommended dosage of HYCAMTIN capsules is 2.3 mg/m 2 /day orally once daily, with or without food, for 5 consecutive days, starting on Day 1 of a 21-day cycle. Round the dose to the nearest 0.25 mg and prescribe the minimum number of 1 mg and 0.25 mg capsules. Prescribe the same number of capsules for each of the 5 dosing days. WebTopotecan Teva 1 mg/1 ml concentrate for solution for infusion 1 ml of concentrate for solution for infusion contains 1 mg topotecan (as hydrochloride). ... 1.5 mg/dl, it is recommended that the full prescribing information be consulted for any advice on cisplatin dose reduction/continuation. If cisplatin is discontinued, there are insufficient ...

Did you know?

WebSep 17, 2024 · A composition according to the present invention can very effectively prevent, ameliorate, or treat gastric cancer, specifically intractable gastric cancer, by screening a subject with suitable generic characteristics for a drug capable of suppressing caveolin-1-mediated endocytosis, and administering the drug into the screened subject. WebTopotecan Teva is an anticancer medicine. It is used on its own to treat patients with: metastatic ...

WebSep 7, 2024 · Topotecan is given intravenously (into a vein) or orally (by mouth). This teaching sheet focuses on the oral formulation. The dosage and schedule is determined by the person’s size, type of cancer, and regimen being used. When administered orally, the capsules should be taken at the same time every day with a glass of water. WebFeb 1, 2024 · WARNING: MYELOSUPPRESSION See full prescribing information for complete boxed warning. Topotecan can cause severe myelosuppression. Administer …

WebJun 9, 2024 · vomiting, stomach pain, loss of appetite, hair loss, weakness, and. tiredness. Tell the doctor if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of Hycamtin. … Web7 rows · These highlights do not include all the information needed to use TOPOTECAN INJECTION safely and ...

Web9 rows · These highlights do not include all the information needed to use HYCAMTIN CAPSULES safely and ...

WebAug 31, 2024 · Reconstitute each 4 mg vial of topotecan hydrochloride for injection with 4 mL sterile water for injection, USP. Dilute the appropriate volume of the reconstituted solution in either 0.9% sodium chloride intravenous infusion, USP or 5% dextrose in water injection, USP. Stability. Because the vials contain no preservative, use contents ... mcglinchey\u0027s bar philadelphiaWebIt was also clastogenic to mouse bone marrow. Topotecan did not cause mutations in bacterial cells. Topotecan given to female rats prior to mating at an intravenous dose of 1.4 mg/m 2 (about equal to the 1.5 mg/m 2 clinical dose based on BSA) caused superovulation possibly related to inhibition of follicular atresia. This dose given to pregnant ... mcglinch \u0026 sons in farmington hills michiganWeb16 HOW SUPPLIED/STORAGE AND HANDLING. Topotecan Injection is supplied in 4 mg/4 mL (1 mg/mL topotecan free base) single-dose vials. Each vial contains 4 mL of the sterile, … libertarian on medicaidWebFULL PRESCRIBING INFORMATION . 1 . INDICATIONS AND USAGE . COSELA is indicated to decrease the incidence of chemotherapy-induced myelosuppression in adult patients when administered prior to a platinum/etoposide-containing regimen or topotecan-containing regimen for extensive-stage small cell lung cancer (ES-SCLC). 2 DOSAGE AND … libertarian news usWebFULL PRESCRIBING INFORMATION WARNING: BONE MARROW SUPPRESSION Do not give Topotecan Hydrochloride for Injection to patients with baseline neutrophil counts less … libertarian on ballot libertarian nonprofitsWebTopotecan is a semi-synthetic derivative of camptothecin and a topoisomerase inhibitor. The chemical name for topotecan hydrochloride is (S)-10-[(dimethylamino)methyl]-4-ethyl … libertarian on spectrum