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Tk6 lymphoblastoid cell

WebDec 1, 2007 · Abstract. The mechanisms of the medium-mediated bystander response induced by gamma-rays in non-irradiated TK6 cells were investigated. Cell cultures were irradiated and the culture medium discarded immediately after irradiation and replaced with a fresh one. In cells incubated with conditioned medium from irradiated cells (CM), a … WebJan 1, 2016 · Abstract Closely related TK6, WTK1, and NH32 human B-lymphoblastoid cell lines differ in their p53 functional status. These lines are used frequently in genotoxicity studies and in studies aimed at understanding the role of p53 in DNA repair. Despite their routine use, little is known about the genetic status of these cells.

Development and validation of an in vitro micronucleus assay platform …

WebMar 11, 2024 · The human lymphoblastoid TK6 cell line was established in 1978 from the parent cell line WI-L2 that was derived from a 5-year-old male with hereditary spherocytosis (Lorge et al., 2016). Due to TK heterozygosity on human chromosome 17 in these cells as well as the presence of the hypoxanthine phosphoribosyltransferase ( HPRT ) gene on the … WebJan 17, 2024 · The TK6 cell line with wild type p53 function was used in our experiments. TK6 cells (human lymphoblastoid cells from spleen) were originally provided by the Tumorbank of the German Cancer Research Center, DKFZ, Heidelberg, Germany. DNA cell line authentication was done by Eurofins Medigenomix Forensik GmbH, Ebersberg, … explain what sql is used for https://simul-fortes.com

Microcolony Size Distribution Assay Enables High-Throughput Cell ...

WebNov 1, 2004 · Induced genomic instability in the human B lymphoblastoid cell line TK6 manifests itself as increases in end-to-end chromosome fusions and non-reciprocal chromosome translocations. It is not associated with elevated frequencies of specific locus mutations or other cytogenetic alterations. WebJul 4, 2012 · Abstract. The Organization for Economic Co-operation and Development (OECD) has recently adopted Test Guideline 487 (TG487) for conducting the in vitro micronucleus (MNvit) assay. The purpose of this study is to evaluate and validate treatment conditions for the use of p53 competent TK6 human lymphoblastoid cells in a TG487 … WebTK6 human lymphoblastoid cells are widely used in the in vitro MN assay as a part of regulatory genotoxicity testing for pharmaceuticals, but have seen relatively limited use in testing of other test materials, including tobacco-related products. As an established cell line, they do not exhibit the donor to donor variability observed in primary cells such as … bubba\u0027s philly cheese steak

Development and Application of TK6-derived Cells

Category:Development and Application of TK6-derived Cells …

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Tk6 lymphoblastoid cell

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WebECACC General Cell Collection: TK6 Product Documents Passage numbers explained MSDS for frozen cell cultures MSDS for Nucleic Acids Important technical information for successful culture of your cells Note: Links open in a new window The Culture Collections represent deposits of cultures from world-wide sources. WebNational Center for Biotechnology Information

Tk6 lymphoblastoid cell

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Webthe human TK6 lymphoblastoid cell line (35), HepG2 cells (36) (37) and primary Syrian Hamster Embryo cells (38) has been described, although they have not been used in validation studies. ... cells analysed are likely to have undergone cell division during or after exposure to the test substance. For WebAdrenocortical carcinoma (ACC) is a rare malignant disease with poor prognosis. The main pharmacological choice, o,p'-DDD (mitotane), produces severe adverse e

WebCell Line Description. The thymidine kinase heterozygote cell line TK6 has been isolated from the lymphoblastoid line HH4. HH4 was derived from the WIL-2 cell line. TK6 cells are … WebATCC human lymphoblastoid tk6 cell line 94 1 9.99 to $1999.99 human lymphoblastoid tk6 cell line - by Bioz Stars , 2024-03 94 / 100 stars Images human tk6 lymphoblastoid cells ( ATCC ) ATCC is a verified supplier ATCC manufactures this product About News Press Release Team Advisors Partners Contact Bioz Stars Bioz vStars Buy from Supplier Images

WebThe implementation of magnetic resonance imaging (MRI) guided radiotherapy (RT) continues to increase. Very limited in-vitro data on the interaction of ionizing radiation and … WebJul 15, 2005 · To detect cell death in the human lymphoblastoid cell line TK6, sub-G 1 DNA content was measured by PI staining and flow cytometry analysis. SPER/NO induced a dose-dependent increase in the sub-G 1 population in TK6 cells, which peaked 2 days after the treatment ( Fig. 1A ).

WebHuman Lymphoblastoid Tk6 Cell Line, supplied by ATCC, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, …

WebAug 1, 1995 · TK6 is a human cell line developed for gene mutation assays and thus may have advantages for human hazard identification and assessment. On the other hand, … bubba\\u0027s playhouseWebWe studied the genotoxicity of ethyl carbamate in Salmonella typhimurium, in Saccharomyces cerevisiae and in human lymphoblastoid TK6 cells. In absence of cytochrome P450 enzymes, no ethyl carbamate-mediated genotoxicity was observed in any of the three test systems in the non-cytotoxic range. In the presence of an activating … bubba\\u0027s playgroundWebCorrigendum for the article Carbon ion and proton beam irradiation of a normal human TK6 lymphoblastoid cell line within a magnetic field of 1.0 tesla Javascript is currently disabled in your browser. bubba\\u0027s phone number