Soluble fas ligand cancer
WebApr 5, 2024 · Introduction. Fas receptor (CD95, tumor necrosis factor receptor superfamily member 6) is a death receptor (DR) localized on the surface of various cells, which triggers a signal transduction pathway … WebSep 28, 2001 · Expression of membrane-bound Fas ligand (mFasL) on colon cancer cells serves as a potential mechanism to inhibit host immune function by inducing apoptosis of …
Soluble fas ligand cancer
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WebJun 1, 2001 · Fas/Fas ligand (FasL) system, a major regulator of apoptosis, is involved in cancer cell death induced by the immune system and anticancer drugs. Fas is a cell … WebJan 22, 2013 · Interestingly, soluble FAS was one of the identified biomarkers that accurately classified cancer patients from those with chronic lung disease. 17 Similarly, comprehensive multiplex assay has been used to identify a panel of serum-based angiogenic and inflammatory biomarkers that predict the clinical benefit of sorafenib and …
WebFeb 15, 2005 · Activation-induced cell death (AICD) is the primary homeostatic mechanism used by the immune system to control T-cell responses, promote tolerance to self-antigens, and prevent autoimmunity. 1-3 Following activation, T cells express Fas and Fas ligand (FasL) and upon repeated antigenic stimulation become sensitive to Fas/FasL-mediated … WebJul 16, 2001 · The serum level of soluble Fas ligand in patients with bladder carcinoma is correlated with both disease progression and increase in tumor grade. In addition, an elevated serum soluble Fas ligand le...
WebThe aim of the study was to examine the concentrations of soluble Fas receptor (sFas) and the soluble ligand for the Fas receptor (sFasL) in serum of women with uterine tumors. ... Straszewski SL, Kamsteeg M, et al. Epithelial ovarian cancer cells secrete functional Fas ligand. Cancer Res 2003; 63: 5573–5581. PubMed Google Scholar ... WebCirculating soluble Fas (sFas) and expression of Fas-ligand on cancer cells are mechanisms of immune escape. The aim of the present study was to investigate expression and …
WebJan 22, 2013 · Inactivation of effector lymphoid cells within the tumor microenvironment and in the peripheral circulation is a potential mechanism of immune evasion by cancer cells. …
WebApr 28, 2004 · Despite the fact that expression of Fas ligand (FasL) in cytotoxic T lymphocytes (CTLs) and in natural killer (NK) cells plays an important role in Fas-mediated … sibket amharic orthodoxWebAbstract. Fas is a transmembrane receptor that can induce apoptosis after cross-linking with either agonistic antibodies or with Fas ligand (FasL). Although originally described as an … the perceptual process includes:WebAbstract. Purpose : The present study was designed to test the therapeutic value of soluble FasL (sFasL) in an acute model of herpetic stromal keratitis (HSK) and, more importantly, a recurrent model of HSK using BALB/c, BALB-lpr, and National Institutes of Health (NIH) mice. Methods : Mice were infected either acutely with the KOS strain of ... sibkl facebookWebNov 22, 2012 · Soluble Fas ligand (sFasL) was quantitated by enzyme-linked immunosorbent assay. The frequency of apoptotic NK cells in gastric cancer patients was significantly higher than in normal controls (p = 0.0016). Moreover, their frequency was related to the progression of gastric cancer. Fas-positive NK cells were significantly more … sibkl lake cityWebJun 10, 2010 · Fas (Apo-1/CD95) and its specific ligand (FasL) are key elements in apoptosis. They have been studied in different malignancies but there are few published studies about the soluble forms of these markers (i.e. sFas/sFasL) in gastric cancer. We have compared the serum levels of sFas/sFasL in gastric adenocarcinoma patients and … the perch alaskaWebJan 22, 2013 · Interestingly, soluble FAS was one of the identified biomarkers that accurately classified cancer patients from those with chronic lung disease. 17 Similarly, … sibiu town hallWebApr 4, 2013 · A recent study employed a multiplex assay of immunologic markers along with mass spectrometry as a screening modality in a patient population at high risk for lung … sibkl service