WebSOFT and TEXT are phase III clinical trials developed in parallel to test the optimal post-operative (i.e. adjuvant) endocrine treatment in premenopausal women with hormone-sensitive early breast cancer. In particular, SOFT has been evaluating the efficacy of adding ovarian function suppression ... WebApr 20, 2024 · Purpose: The Tamoxifen and Exemestane Trial (TEXT)/Suppression of Ovarian Function Trial (SOFT) showed superior outcomes for premenopausal women with …

Adjuvant Ovarian Suppression in Premenopausal Breast …

WebIn 2014, the long awaited results of the International Breast Cancer Study Group (IBCSG) led randomized, phase 3 trials, Suppression of Ovarian Function Trial (SOFT) and Tamoxifen … Webtion Trial (SOFT) and the Tamoxifen and Exemes - tane Trial (TEXT), involving premenopausal women with hormone-receptor–positive early breast cancer. SOFT was … how to get to tromso from uk

SOFT & TEXT Achievements Breast International Group

WebThe SOFT and TEXT clinical trials produced practice changing results in the treatment of breast cancer in young women, who may have a poorer long-term prognosis. The research … WebThe NaturalVue (etafilcon A) Multifocal 1 Day contact lens is a unique, patented, center-distance, extended depth of focus design, with an 8.3mm base curve, a 14.5mm lens diameter, a power range from +4.00D to −12.25D, and a universal add. The NVMF lenses incorporate an extended depth of focus design with up to 20 diopters (D) of relative ... WebSep 27, 2024 · Several trials evaluated the role of ovarian function suppression for the adjuvant treatment of premenopausal patients with hormone receptor-positive early breast cancer. Based on the results of the SOFT and TEXT trials, international guidelines recommend the addition of ovarian function suppression to standard adjuvant endocrine … how to get to trueshot lodge shadowlands