Sigma-1 receptor wikipedia
WebReceptor sigma-1, σ1R – jeden z dwóch znanych podtypów receptorów sigma.Początkowo traktowany razem z receptorem sigma-2 jako receptor opioidowy, po sklonowaniu genu … The sigma-1 receptor (σ1R), one of two sigma receptor subtypes, is a chaperone protein at the endoplasmic reticulum (ER) that modulates calcium signaling through the IP3 receptor. In humans, the σ1 receptor is encoded by the SIGMAR1 gene. The σ1 receptor is a transmembrane protein expressed in many … See more The σ1 receptor is defined by its unique pharmacological profile. In 1976 Martin reported that the effects of N-allylnormetazocine (SKF-10,047) could not be due to activity at the μ and κ receptors (named from the … See more The mammalian σ1 receptor is an integral membrane protein with 223 amino acids. It shows no homology to other mammalian proteins but strikingly shares 30% sequence identity … See more σ1 receptor knockout mice were created in 2003 to study the effects of endogenous DMT. Strangely, the mice demonstrated no overt phenotype. As expected, however, they did lack … See more • Sigma-2 receptor See more A variety of specific physiological functions have been attributed to the σ1 receptor. Chief among these are modulation of Ca … See more Mutations in sigma-1 receptor have been associated with distal spinal muscular atrophy type 2. See more The following ligands have high affinity for the σ1 receptor and possess high binding selectivity over the subtype σ2: • PRE-084 • ANAVEX2-73 See more
Sigma-1 receptor wikipedia
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WebPress J to jump to the feed. Press question mark to learn the rest of the keyboard shortcuts WebA method for reducing pathological cardiac hypertrophy and/or inducing physiological cardiac hypertrophy by administering Nigella sativa or an extract thereof to a subject in need thereof, especially to an athletic subject in order to reduce exercise-induced pathological cardiac hypertrophy. A composition comprising Nigella sativa for use in said method.
Webmammalian protein found in Homo sapiens Web218-229-1 PubChem: 2353: DrugBank: DB04115: ... La berberina è ligando agonista del recettore sigma-1 e 2 ed è anche un agonista del PPARγ (Peroxisome proliferator …
Webو. تجربه نزدیک به مرگ (به انگلیسی: Near-death Experience) (بهصورت مخفف: NDE) نوعی تجربه شخصی عمیق است که مرتبط با مرگ یا نزدیک به آن میباشد و طبق ادعاها، مشخصات مشابهی دارند. این تجربه ممکن است شامل تجربه ... WebOpioide. Opi cru, d'on deriven la majoria dels opiacis. Un opioide és qualsevol agent que s'uneix a receptors opioides situats principalment al sistema nerviós central i en el tracte …
WebSigma-1 receptor je transmembranski protein koji je izražen u mnogim tipovima tkiva. On je posebno koncentrovan u pojedinim regionima centralnog nervnog sistema. Za njega se …
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