Phospho stat4
WebJun 15, 2001 · The decrease of STAT4 protein appears to be due to specific degradation of phospho-STAT4, possibly through the proteasome degradation pathway. Decreased levels of STAT4 protein lead to decreased STAT4 DNA-binding activity and reduced proliferation and secretion of IFN-gamma. This down-regulation of STAT4 is specific for IL-12 … WebJun 3, 2005 · IL-12-induced STAT4 phosphorylation and IFN-production and enhances IFN--induced STAT4 activation and IL-10 production. These effects are associated with a down-regulation of IL-12R1 ex-pression but an up-regulation of IFN-R. These results indicate that the effect of glucocorticoids on the STAT4 signaling pathway depends on the stim-
Phospho stat4
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WebBioTNT是一家专业提供生命科学分子生物学、蛋白质组学、免疫学等相关产品和服务的生物技术服务公司,包括抗体、蛋白、多肽、ELISA、生物芯片、Real Time PCR等等。BioTNT的仪器,试剂耗材和服务帮助研究人员提高科学研究能力,推动新的研究和开发,以便不断地改善人类的生活。 WebA nuclear phospho-tyrosyl phosphatase TC-PTP has been shown to dephosphorylate STAT1. STAT1 is exported back to the cytoplasm and this terminates STAT1-stimulated gene expression. ... The STAT4 and STAT1 genes are neighbors on chromosome 2 and encode proteins that belong to a family of transcription factors originally isolated by their …
WebPolyclonal Antibody for studying Stat4 (Tyr693) phosphate. Cited in 17 publications. Validated for WB, IP, ChIP. Highly specific and rigorously validated in-house, Phospho … WebApr 14, 2024 · Phospho-STAT3 (Y705) Antibody - Prepare a 100X working concentration of the antibody by reconstituting with 110 L of 1X PBS. After reconstitution, store at 2-8° C for up to 30 days or aliquot and store at -20° C in a manual defrost freezer for up to 60 days.* Total STAT3 Antibody - Prepare a 100X working concentration of the antibody by
WebUnconventionally, during RNA virus infection, STAT4 was found unphosphorylated in the cytoplasm of macrophages. Mechanistically, STAT4 interacts with E3 ligase CHIP, which … WebDec 21, 2012 · We used immunohistochemistry with phospho-specific antibodies to look at the presence of activated JAK2 and STAT3 in human tissues, BTSCs, and tumors from …
WebThe Phospho-STAT4 (Tyr693) assay provides a quantitative measure of the data obtained with the traditional Western blot. Phospho -STAT4 (Tyr693) Kit Kit Size Catalog # 1 plate K150PAD-1 5 plates K150PAD-2 25 plates K150PAD-4 20 µg lysate per lane MSD Phosphoprotein Assays
WebCell-Based phospho-STAT ELISA Samper Kit for detecting phospho-STAT1 (pTyr 701), phospho-STAT3 (pTyr 705), and phospho-STAT5 (pTyr 694) in cultured cell lines 检测培养细胞系中磷酸化-STAT1(pTyr(pTyr 701),磷酸化-STAT3 (pTyr 705), 和磷酸化-STAT5 (pTyr 694)的基于细胞的ELISA试剂盒 side effects to chemo and radiationWebHuman Phospho-STAT4 (Y693) Antibody Summary Species Reactivity Human Specificity Detects human STAT4 when phosphorylated at Y693. Source Polyclonal Rabbit IgG Purification Antigen Affinity-purified Immunogen Phosphopeptide containing human Phospho-STAT4 Y693 site Formulation Lyophilized from a 0.2 μm filtered solution in PBS. the plane in spainWebPhospho-MAPK Family ELISA Sampler Pack Pim Kinase ELISA Sampler Pack Pyroptosis ELISA Sampler Pack Reactive Cell Death and Autophagy ELISA Sampler Pack Reactive Inflammasome ELISA Sampler Pack Receptor Tyrosine Kinase ELISA Sampler Pack SARS-CoV-2 Virus-Host Interaction ELISA Sampler Pack the plane is comingWebActivation of the transcription factor signal transducer and activator of transcription (STAT)‐4 is critical for the differentiation of T‐helper 1 cells/type‐1 cytotoxic T‐cells and the production of interferon (IFN)‐γ. Expression of STAT4, phospho‐STAT4, IFN‐γ and T‐box expressed in T‐cells (T‐bet) proteins in bronchial biopsies and bronchoalveolar lavage … side effects to constipationWebThe BD Pharmingen™ Transcription Factor Phospho (TFP) Buffer Set is designed to enable robust and simultaneous flow cytometric analysis of various cell surface antigens, transcription factors, and phosphorylated signal proteins in cells derived from both human and mouse tissues. side effects to creatineWebA key component in the activation of Stat4 is the phosphorylation on tyrosine and serine residues in response to IL-12 stimulation. IL-12 stimulation leads to the phosphorylation … the plane in top gunWebKeyTec®TR-FRET Phospho-STAT4 (Y693) Kit : KeyTec®TR-FRET Phospho-STAT5 (Y694/Y699) Kit : KeyTec®TR-FRET Total STAT5 Kit : KeyTec®TR-FRET Phospho-STAT6 … the plane is flying