WebNov 1, 2024 · In macrophages, HDAC6 is involved in regulating the expression of inflammatory factors through the MAPK-NF-κB/AP1 signaling pathway (Zhang et al., 2024). During HIV-1 infection, inflammation of the CNS contributes to the development of AIDS-related diseases. HDAC6 activates the MAPK-NF-κB/AP1 signaling pathway or NADPH … WebEmail [email protected]; [email protected]. Background: The glycolysis pathway of M1 macrophages is a key factor affecting the inflammatory response. The aim of this article is to investigate the role of histone deacetylase 6 (HDAC6) in the M1 macrophage glycolysis pathway during acute liver failure (ALF).
Frontiers HDAC6 Mediates Macrophage iNOS …
WebHDAC6 is a direct target gene of miR-22 in macrophages According to computational analysis, HDAC6 has a 7-nt seed region which is complementary to miR-22 within its 3’UTR ( Fig. 1B ). To determine whether HDAC6 is a direct target of miR-22, we cloned wild type- or mutant 3’UTR of HDAC6 into a luciferase reporter and then performed ... WebOct 21, 2024 · The data showed that HDAC6 expression was positively correlated with colon cancer metastasis and the tumor stage (Table 1), and that the proportion of … im4led ice maker
The Role of HDAC6 in Autophagy and NLRP3 Inflammasome
WebWe're excited that so many posters will be featuring PhenomeX's breakthrough technology at AACR this year! Check out these amazing posters at the poster… WebOct 27, 2024 · The Role of HDAC6 in Autophagy. Autophagy, specifically macroautophagy, is a conserved self-eating process that is vital for cellular homeostasis and delivery intracellular components, including soluble proteins, aggregated proteins, organelles, macromolecular complexes, and foreign bodies for degradation ().This … WebOct 27, 2024 · The Role of HDAC6 in PTM of Autophagy-Related Transcription Factors. PTM of autophagy-related transcription factors (), such as transcription factor EB (TFEB) … im 50 but look 35